CAH educational info

[Sunshine1]

The post CAH educational info about eight or so post down might help people understand CAH more.

[fraulein_Maria]

http://www.vivo.colostate.edu/hbooks/pathphys/endocrine/basics/steroidogenesis.html

this link shows all KNOWN forms of CAH.

[neko2]

Actually no, those are steroidogenic enzymes, not necessarily all forms of CAH. eg aromatase deficiency is not CAH.

The forms of CAH that I know of are:

21-hydroxylase
3beta-HSD
17alpha-hydroxylase
11beta-hydroxylase
P450 oxidoreductase
StAR
P450scc/CYP11A1 (extremely rare)

I guess you could include aldosterone synthase, but that's really just salt-losing and not cortisol-deficient CAH.

[Rycharde]

Is there anywhere I can read summaries of the types of CAH?

I find it very hard for me to learn by reading as I get very easily distracted and can not focus on the information enough to learn it. It has been difficult for me to understand the difference between the types of CAH by reading the scientific articles I have found on the internet.

Thanks for all your help.

[fraulein_Maria]

Actually no, those are steroidogenic enzymes, not necessarily all forms of CAH. eg aromatase deficiency is not CAH.

>>> yes, i knew what they were Neko.
in case it escaped your notice, all forms of CAH are named after the enzyme deficiency that causes it. If we really want to pick nits, you should have listed them by frequency of occurance begining with the most common... 21 would be first, but 11 beta would be second. <<<

The forms of CAH that I know of are:

21-hydroxylase
3beta-HSD
17alpha-hydroxylase
11beta-hydroxylase
P450 oxidoreductase
StAR
P450scc/CYP11A1 (extremely rare)

I guess you could include aldosterone synthase, but that's really just salt-losing and not cortisol-deficient CAH.

>>> including aldosterone synthase makes even less sense than including aromatase if we define CAH as primarily something that causes virilization. <<<

[fraulein_Maria]

[QUOTE=Rycharde;13247]Is there anywhere I can read summaries of the types of CAH?

try wikpedia :)

[Rycharde]

Wikipedia "Duh!":happydanc