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Unread 10-23-07, 04:46 PM
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fraulein_Maria fraulein_Maria is offline
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Join Date: Mar 2006
Location: Peterborough, NH
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Quote:
Originally Posted by JOS View Post
I don't mind you being interested
I'm actually quite worried now about the fact that I've been taking the oestrogens in tablet form now.... apparently patches are better for your liver

>>> yes. the patches have ethynyl estradiol... easily absorbed through the skin, so it by-passes the "first pass" (the digestive tract) through the liver. this means you can take a much lower dose and still have the same effect.
During the "first pass" much of the hormone is treated like a poison (this is true of most drugs aswell) and converted into something that can be easily excreted. this is very stressful to your liver.
Beyond that its good for your liver, its also better for your other tissues aswell. with pills, you get a "see-saw" effect... very high, then very low then very high again. this is not how our bodies are designed to work. our bodies need a steady increase and/or a steady decrease to function properly. that's why both under and over dosing of a hormone will cause nausea. <<<

but I tried them once and found that my clothes got more treatment that I did.... I must wriggle a lot LOL.

>>> lol, indeed. perhaps you might want to place the patch on a body part that "wiggles" less? for me, that was my belly. have you tried your upper thigh? <<<

But I wonder if the fact that I still had a testicle (possibly producing testosterone) was I infact 'doubling up' on my dose... I think I'm right that testosterone can get converted into oestrogens...????

>>> 2 related thoughts... one at a time.

first: yes, your testis is making testosterone that is being converted into estrogen.

second: but no, your not doubling up.

How can this be? Your body is using the natural estrogen up first. Your doctor may have decided (and maybe you want to talk to him/her about this) that your liver is not converting enough test. to est. to maintain your feminity or that your remaining testis is not producing enough test. to maintain your bones. so from the doctor's point of view, the pills are SUPPLIMENTING your testis, not replacing them. someone in the Klinefelter's forum posted a very erudite description of the blood levels necessary for each hormone to maintain bone, and i defer to them on the details. <<<

And I don't want you to think I'm sexed obsessed or anything, that was just one difference I noticed but I don't feel quite the same as I did when I was really depressed.... more kind of tired...

>>> no, you do not come off that way. (least not to me) never apologize for enjoying the body you have. It does not surprise me that you feel this way. Since i've been on prednisone (the treatment for CAH which lowers my test. level) i find myself more prone to depression. in addition to being the hormone mainly responsible for "drive" (both sexual and initiative) and aggression, it also affects (positively) our sense of well-being.
in my case (in the case of all CAH i dare say) that sense of well-being is at best exaggerated, at worst illusionary, but that's mainly true because we suffer from an EXCESS. You are probably truely deficient.
Remember, when doctors speak of your tissues being androgen insensitive, they are NOT including one very important tissue.... your brain. fatty tissues (brain, nerves, gonads, skin) do not need receptors for hormones to respond to them. think of receptors as doors. Your cells are missing the doors (or in PAIS, the locks on the doors are broken so test. can't get in) marked "androgens". BUT, fatty tissue doesn't need doors... like ghosts, hormones pass right through the walls! <<<

sorry self obsessing again... really bad habit, sorry
Jos
>>> no hon. its ok. its not obsessing. we need to talk about these things with SOMEONE... preferably with someone who's been there. Though AIS'ers and CAH's are physical opposites, what we have in common is how society and the doctors treat us... reason enough to hang together <<<
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